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From the White House and the Supreme Court on down, gay rights advocates have won a string of victories this year. Many Americans remain opposed to same-sex marriage, but support for gays and gay marriage has been rising — particularly among young people.

A visibly shocked James McBride picked up the fiction prize for his novel The Good Lord Bird about a young slave who joins up with abolitionist John Brown. The nonfiction award was won by George Packer for The Unwinding: An Inner History of the New America.

One of the nation's largest school systems has been pushed to the brink of insolvency. Not long ago, Philadelphia was touted as a "laboratory of innovation," a promising model for urban public education. But something went wrong. So who is responsible for the district's descent into academic and financial ruin?

Many organic farmers are hopping mad at the U.S. Food and Drug Administration. Their reason? Fertilizer. The FDA, as part of its overhaul of food safety regulations, wants to limit the use of animal manure, which organic farmers call a precious resource and a basis of their farming practices.

Nobel Prize winning biochemist Fred Sanger has died. He was 95. Sanger, who won two Nobel Prizes, pioneered research into the human genome. Steve Inskeep and Renee Montagne have this remembrance.

Fort Dodge, Iowa, is not exactly what you'd think of as a hotbed of health care innovation. But the small town in the western part of the state is part of a Medicare pilot project that economists say could be a pathway to the holy grail of health care: providing better care at a lower cost.

Dallas became known as the "City of Hate" after President John F. Kennedy was killed there. But the city has changed, and it hopes that the 50th anniversary of the assassination on Friday will be a chance to show the extent of that transformation.

After gaining 109 points Thursday, the Dow Jones industrial average closed above 16,000 for the first time in history. The index touched the mark earlier this week but fell short by day's end.

By putting light sensors inside a giant ice cube that's a mile beneath the South Pole, scientists detected 28 neutrinos from beyond the solar system. It's just a start – but researchers hope the work could eventually yield a way to see through debris clouds to the core of exploding stars.

There might be tens of thousands fewer smokers in Central New York thanks to county and state policies that have proven to curb tobacco use. Today is the…